Fusion Lumos
Instrument Overview
Fusion Lumos is Thermo Fisher’s high-end Tribrid mass spectrometry platform, integrating a quadrupole, linear ion trap, and Orbitrap analyzer. It is designed for high-resolution, high-sensitivity, multi-stage fragmentation analysis of complex biological samples, supporting proteomics, PTM studies, metabolomics, and small-molecule analysis with rapid scanning, high throughput, and low-abundance molecule detection.
Key Features
- Tribrid architecture combines quadrupole, linear ion trap, and Orbitrap technologies to balance sensitivity, speed, and resolution.
- High sensitivity enables accurate detection of low-abundance proteins and metabolites.
- Ultra-high Orbitrap resolution enables accurate mass measurement and isotope peak separation.
- Multiple fragmentation modes, including CID, HCD, and ETD, support PTM analysis and structural characterization.
- High-throughput quantification supports isotope-label quantification, PRM, and multi-sample analysis.
Platform Applications
- Proteomics: whole-proteome identification, differential expression analysis, and low-abundance protein detection
- PTM studies: identification and localization of phosphorylation, acetylation, ubiquitination, glycosylation, and other PTMs
- Top-down protein analysis: intact protein sequencing and isoform analysis
- Biopharma: antibody and protein-drug analysis, host-cell protein analysis, and impurity analysis
- Clinical and translational research: biomarker screening, disease-mechanism studies, and precision-medicine sample analysis
Shenzhen Wininnovate Bio Co., Ltd.
Innovative mass spectrometry and AI technologies provide protein and metabolite mass spectrometry multi-omics solutions for life science research, empowering the growth of the biotechnology, pharmaceutical, and healthcare industries.
